July 11th
A simple eye-tracking tool for assessing MS disease severity
This study reports preliminary data on a new clinical assessment tool, where patients perform a variety of oculomotor tasks using an iPad Pro.
June 2023 preprints
Linking gut microbiome to disease progression in MS
This study identified components of the gut microbiome that were predictive of subsequent worsening of EDSS scores, providing a potential biomarker of patients most in need of aggressive interventions.
PFOS accumulates in myelin and blocks remyelination
In this study, PFOS accumulated in the myelin of mouse pups whose mothers were given the chemical during gestation and lactation; it also blocked remyelination in an in vitro assay.
Tying HLA genotype to MS severity in humanized mice
This study of found that humanized mice showed differences in CNS lesion load depending on the HLA genotype of the human donor and their disease status.
