“Identification of Rare Damaging Missense and Loss of Function Variants in GWAS Loci Using Genome Sequencing Data from Two...
Risk Factors
“Psychotic symptoms are associated with elevated tau PET signal in the amygdala independent of Alzheimer’s disease clinical severity and...
“Rare genetic variation in Fibronectin 1 (FN1) protects against APOEe4 in Alzheimer’s disease.” Prabesh Bhattarai, et al. – Columbia...
“An Alzheimer’s disease-associated common regulatory variant in PTK2B has causal effects on microglial function.” Erica Bello, et al. –...
“Polygenic burden of short tandem repeat expansions promote risk for Alzheimer’s disease.” Michael Guo, et al – University of...
“Uncoupling of synaptic loss from amyloid burden by an Alzheimer’s disease protective variant of PLCγ2.” Ryan J. Bevan, et...
“APOE loss-of-function variants: Compatible with longevity and associated with resistance to Alzheimer’s Disease pathology.” Augustine Chemparathy, et al. – Stanford...
“Functional variations in gamma-secretase activity are critical determinants of the clinical, biomarker, and cognitive progression of autosomal dominant Alzheimer’s...
“The MIND diet, brain transcriptomic alterations, and dementia.” Jun Li, et al. – Brigham and Women’s Hospital. “Therapeutic potential...
“Resilience to autosomal dominant Alzheimer’s disease in a Reelin-COLBOS heterozygous man.” Francisco Lopera, et al. – University of Antioquia,...